Aspirin is prepared by acetylating salicylic acid in a process called esterification. The polar oxygen accepts the electrons from now positively charged hydrogen. The final burette readings were recorded. It is recommended that aspirin should not be given to children or teenagers as pain relievers if they have the flu, chicken pox, or a cold. Eyes: Glasses and contact lenses since 1996.
The weight of the recovered sample was 2. Our purity percentage was 99. Acetic acid, Acid, Acid dissociation constant 1228 Words 4 Pages Experiment 2 and 3: Synthesis of Aspirin and Determination of Melting Point A. The protonation of the aldol took place followed by the hydroxide groups have been eliminated as leaving groups. The results I used where the published value of what temperature pure aspirin melts at, the temperature my aspirin sample melted at, the weight of pure aspirin and the weight of impure aspirin. He can initiate it by forming two teams, dividing up the class, and initiating a competition among them. Our sample mass was 0.
After the sample has dried for 5 minutes, turn off the vacuum filtration apparatus and retrieve the purified product from the Buchner funnel and place it in the previously weighed weigh boat. For part B synthesis of Nylon 6, 10 , when sebaceous chloride was added to Noah in 1, 6-hexadecimal, two layers was generated with little gas. A pure compound has a specific range in which it melts and it is normally a fairly small range. The interface Nylon 6,1 0 was pulled out between organic and aqueous layer with a bent spatula. When mixing Noah and sebaceous chloride, two layers were formed. For better chemical reaction, there should be large surface area for chemical absorption process to get chemical reaction. The white film was produced from the surface when the solution was filtered.
The first part of the experiment aims to synthesize aspirin from the reaction of salicylic acid with acetic anhydride with the aid of phosphoric acid as a catalyst. Next a melting point test was performed on the purified aspirin product. If crystallization does not occur use a glass stirring rod and with strong force scratch the bottom of the Erlenmeyer flask. It is an acetyl derivative of salicylic acid. Organic chemists began working with willow bark and many other plants to try and extract and isolate the active ingredients from them, in doing so it was found that the active ingredient was salicylic acid. The percent yield of the purified aspirin product was 5.
After some anhydrous Nassau were added, the solution became like glue. To while time away and to just simply be entertained and drawn out of the cruel realities and boring routines of life, one is often enticed by these seemingly harmless and even amusing stories. Next a phenol test was performed on the crude aspirin product, the purified aspirin product, and salicylic acid as a control. She is married and has three children. This is to prevent the reaction of acetic anhydride with water at the start of the experiment, if this had happened, no aspirin could have formed. This was done prior to the start of part 2 of this lab. The ethanol acts as a solvent which allows the acetone and benzaldehyde to dissolve and react with each other.
So, there is ration of 1:1. Pour the contents in the 25 mL Erlenmeyer flask into a Buchner funnel attached to a vacuum filtration apparatus. Other potential causal variables are elevated defective esophageal clearance and intra-abdominal pressure. The history of aspirin began in 1763 when Edward Stone wrote a paper to the Royal Society of London that claimed that willow bark could cure ague, which is now known as malaria. Purification is needed to eliminate any salicylic acid and acetic anhydride that did not react, as well as the acetic acid product and phosphoric acid. The layers were then stirred vigorously to obtain a ball of nylon and dried.
The patient says that the pain is severe during the morning and the night times, and majorly during the cold weather. Much of this is believed to be due to decreased production of prostaglandins and thromboxanes. Denies history of recent travels. After heating the mixture for 5 minutes, gravity filter what is in the 25 mL Erlenmeyer flask through filter paper. Garcia presents with sudden abdominal pain.
The melting point of the purified product was lower than the expected 135 degree Celsius melting point of aspirin, which revealed to us that the purified aspirin product still contained some impurities. Industry takes advantage of the same reaction but conducts it in larger scale. So, aluminum sheet was cut into tiny pieces but there were still large pieces in the beaker which may cause error, as chemical reaction do not went properly. This is because the heat energy in the precipitate easily to be released since the precipitation formation is an exothermic reaction and hence it maximizes the formation rate of the product. The beaker was placed on the hot plate. In this experiment aspirin, also known as acetylsalicylic acid, was synthesized from salicylic acid and acetic anhydride.